Sodium and Water Homeostasis, Volume 1

general immunological disturbance is one of the questions considered in this book, but not fully answerable as yet. There are two ways in which a review of this kind might be written, one comprehensively with a maximum of sources cited and a minimum of personal bias interjected, the other analytically with sources selected and interpreted in the light of the author's opinions. Fraser and Martin manage to steer a middle course. The body of each chapter is reasonably comprehensive and objective, but each chapter is introduced by a summary in which conclusions are stated, and each is followed by a comment section in which controversial points are evaluated and suggestions made for further work. The book contains a good review of the available biochemical data on measles virus and treats extensively the pathological relationships between virus and various host cells. It deals fully with the SSPE picture and treats rather completely the relationship to MS. It covers immunological responses to the virus well, but deals not at all with the problem of immunizing the very young and reducing measles incidence in various sociological settings. It is a book that will be very useful to the specialist, but it is also a book designed for those with a concern for the application of basic experimental data to disease etiology. It provides a firm and substantial footing on which to develop the hypotheses relating persistent infection to chronic diseases such as MS, Hodgkins, Paget's bone disease, and various tumors.